Search results for " Nucleophilic aromatic substitution"

Synthesis of aryl azides: A probe reaction to study the synergetic action of ultrasounds and ionic liquids

2011

Abstract The combined effect of ultrasounds and ionic liquids was used to perform the synthesis of aryl azides by nucleophilic aromatic substitution in ionic liquid/[1-butyl-3-methylimidazolium][N 3 ] binary mixtures. The ultrasounds efficiency was analyzed as a function of the substrate and of the ionic liquid structure. In the first case, both 6π and 10π electrons aryl halides were considered. As far as the ionic liquid structure is concerned, both aromatic and aliphatic ionic liquids were taken into account. Among aromatic cations, the effects due to different ability in giving hydrogen bond or π–π interactions were considered. The use of a geminal ionic liquid having an aromatic spacer …

Miscela binaria liquido ionico/[bmim][N3]: un mezzo efficace per la sintesi di arilazidi mediante SNAr

Study of aromatic nucleophilic substitution with amines on nitrothiophenes in RTILs: are the different effects on the behavior of para-like and orto-…

2006

The kinetics of the nucleophilic aromatic substitution of some 2-L-5-nitrothiophenes (para-like isomers) with three different amines (pyrrolidine, piperidine, and morpholine) were studied in three roomtemperature ionic liquids ([bmim][BF4], [bmim][PF6], and [bm2im][BF4], where bmim ) 1-butyl-3- methylimidazolium and bm2im ) 1-butyl-2,3-dimethylimidazolium). To calculate thermodynamic parameters, a useful instrument to gain information concerning reagent-solvent interactions, the reaction was carried out over the temperature range 293-313 K. The reaction occurs faster in ionic liquids than in conventional solvents (methanol, benzene), a dependence of rate constants on amine concentration sim…